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BRIEF RESEARCH REPORT article

Front. Neurol.
Sec. Stroke
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1500451
This article is part of the Research Topic Cerebral cavernous malformations View all 3 articles

Use of Balloon Angioplasty for Patients with Intracranial Large Atherosclerotic Acute Ischemic Stroke and Cerebral Cavernous Malformation: A Case Report

Provisionally accepted
Yiwan Wang Yiwan Wang Tianyu Wang Tianyu Wang Jiangmin Liang Jiangmin Liang *
  • Taizhou Central Hospital, Taizhou, China

The final, formatted version of the article will be published soon.

    Thus far, clinical data relating to the treatment of cerebral cavernous malformation (CCM) patients with acute stroke (AIS) are incredibly scare due to the low incidence of CCM. Furthermore, the safety profile of using tissue plasminogen activator, the only drug approved for AIS treatment within 4.5 hours, remains controversial in patients with CCM. Recently, balloon angioplasty has been reported as a successful treatment for intracranial large atherosclerotic AIS patients. In our department, we treated a patient with intracranial large atherosclerotic AIS and CCM using balloon angioplasty, resulting in a positive outcome. Here, we discuss the safety and efficiency of balloon angioplasty for the treatment of intracranial large atherosclerotic AIS in patients with CCM. In conclusion, we suggest that balloon angioplasty may be a potentially safe and effective treatment for intracranial large atherosclerotic AIS patients with CCM. However, further research is needed to explore the use of mechanical revascularization in AIS patients with CCM.

    Keywords: balloon angioplasty, intracranial large atherosclerotic, acute stroke, Cerebral cavernous malformation, case report

    Received: 23 Sep 2024; Accepted: 06 Jan 2025.

    Copyright: © 2025 Wang, Wang and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jiangmin Liang, Taizhou Central Hospital, Taizhou, China

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