Lin Wu ¹ Fuqing Zhou ^1* Meng Li ²

• ¹ The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China
• ² University Hospital Jena, Jena, Thuringia, Germany

The second manuscript, "Amygdala and cognitive impairment in cerebral small vessel disease: structural, functional, and metabolic changes" (https://doi.org/10.3389/fneur.2024.1398009), explores the role of the amygdala in cognitive impairment associated with cerebral small vessel disease. This manuscript also explore how new neuroimaging methods can assess amygdala changes early, laying a foundation for future comprehensive exploration of the pathogenesis of cerebral small vessel disease, offering new insights into the pathophysiology of vascular cognitive impairment.The third manuscript, "Hypo-connectivity of the primary somatosensory cortex in Parkinson's disease: a resting-state functional MRI study" (https://doi.org/10.3389/fneur.2024.1361063), investigates the connectivity of the primary somatosensory cortex in Parkinson's disease. This study provides valuable insights into the sensorimotor network disruption in PD, contributing to the understanding of non-motor symptoms and their impact on quality of life for patients.Finally, the fourth manuscript, "Altered regional neural activity and functional connectivity in patients with non-communicating hydrocephalus: a resting-state functional magnetic resonance imaging study" (https://doi.org/10.3389/fneur.2024.1438149), examines the neural activity and connectivity in patients with non-communicating hydrocephalus. The findings point to the disrupted regional neural activity and functional connectivity are altered in patients with non-communicating hydrocephalus and are correlated with cognitive impairment in cognitive impairment, advancing our understanding of the pathophysiological mechanisms underlying the association between non-communicating hydrocephalus and cognitive impairment.In summary, the articles featured in this research topic showcase the transformative potential of functional MRI in advancing our understanding of CNS diseases. They highlight the importance of multimodal imaging techniques in uncovering the complex neural substrates underlying cognitive impairments, and they set the stage for future research that will undoubtedly lead to improved diagnostic accuracy, more effective treatments, and ultimately, better patient outcomes. We are grateful to all the authors for their groundbreaking contributions and look forward to witnessing the continued growth and evolution of this exciting field.