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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Neurotechnology
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1513867

Temporary Trigeminal Ganglion Stimulation Can Improve Zoster-Related Trigeminal Neuralgia: A Retrospective Study In A Single Center

Provisionally accepted
Kan Yue Kan Yue Shengrong Xu Shengrong Xu Xin Hu Xin Hu Junhong Li Junhong Li Ruilin He Ruilin He Zongbin Jiang Zongbin Jiang *
  • department of pain management, The Second Affiliated Hospital of Guangxi Medical University, Nanning City, China

The final, formatted version of the article will be published soon.

    Conventional management approaches have been challenged in dealing with zoster-related trigeminal neuralgia. Percutaneous trigeminal ganglion stimulation (TGS) has been rarely reported as a potential treatment option for alleviating pain associated with this condition. The present study investigated the application of percutaneous TGS in a series of patients suffering from Zoster-related trigeminal neuralgia to evaluate its potential efficacy of pain relief. We retrospectively reviewed the medical records of all patients who underwent TGS at the Department of Pain Management, Second Affiliated Hospital of Guangxi Medical University. All patients were followed for up to six months. Clinical data, including the Visual Analog Scale (VAS), Pittsburgh Sleep Quality Index (PSQI), and medication consumption were recorded before and after treatment. Adverse events related to the treatment were also documented. A total of nine patients underwent percutaneous TGS for Zoster-related trigeminal neuralgia. Among these patients, five (56%) experienced more than 50% pain relief at discharge. At the six-month follow-up, the mean VAS score decreased from preoperative 6.1±1.5 to 2.5±1.9, demonstrating a statistically significant 3 reduction (t = 4.36, P < 0.05 ). The PSQI also showed a significant reduction from a baseline score of 14.1 to 6.5 at the six-month follow-up ( Z = 4.2, P < 0.05). Seven patients reported satisfaction with the treatment and no serious adverse events occurred. The results of the present study suggest that this contributes growing evidence that percutaneous TGS may be an effective treatment for Zoster -related trigeminal neuralgia.

    Keywords: Trigeminal Ganglion Stimulation, zoster-related trigeminal neuralgia, trigeminal postherpetic neuralgia, varicella-zoster virus, Neuromodulation

    Received: 19 Oct 2024; Accepted: 20 Dec 2024.

    Copyright: © 2024 Yue, Xu, Hu, Li, He and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zongbin Jiang, department of pain management, The Second Affiliated Hospital of Guangxi Medical University, Nanning City, China

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