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REVIEW article

Front. Neurol.
Sec. Epilepsy
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1503025

Intravenous Push Administration of Anti-seizure Medications

Provisionally accepted
Raniah Aljadeed Raniah Aljadeed 1,2*Brian W. Gilbert Brian W. Gilbert 3Tallib Karaze Tallib Karaze 4Megan A Rech Megan A Rech 4
  • 1 King Saud University, Riyadh, Saudi Arabia
  • 2 King Saud Medical City, Riyadh, Saudi Arabia
  • 3 Wesley Medical Center, Wichita, Kansas, United States
  • 4 Loyola University Medical Center, Maywood, Illinois, United States

The final, formatted version of the article will be published soon.

    Intravenous push (IVP) administration of anti-seizure medications is becoming increasingly popular among emergency departments. IVP administration eliminates the need for compounding and preparation by the pharmacy department, as well as the need to gather infusion materials or set up a patient’s tubing and pump, all of which translate to faster drug administration. This is important given the time-sensitive nature of status epilepticus treatment. This review will discuss several anti-seizure medications, including phenytoin, fosphenytoin, valproic acid, levetiracetam, brivaracetam and lacosamide, for which evidence supports the safe and efficacious use of IV push administration.

    Keywords: Antiepileptic (AEDs), intravenous push, Status Epilepticus, Anti-seizure medications, anti-seizure medications (ASMs), Intravenous infusion

    Received: 27 Sep 2024; Accepted: 30 Dec 2024.

    Copyright: © 2024 Aljadeed, Gilbert, Karaze and Rech. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Raniah Aljadeed, King Saud University, Riyadh, Saudi Arabia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.