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ORIGINAL RESEARCH article
Front. Neurol.
Sec. Stroke
Volume 15 - 2024 |
doi: 10.3389/fneur.2024.1501316
This article is part of the Research Topic Quality of Stroke Care: What Could Be Improved, and How? - Volume II View all articles
Evaluation of Circadian Rhythm and Prognostic Variability Pre-and Post-CEA or CAS Treatment in Patients with Carotid Artery Stenosis
Provisionally accepted
Yi Quan
1*
Zhongzhu Wang
2
Tao Zhang
2
Yanyong Sui
2
Xin Zhang
2
Xueliang Ji
2
Ao-fei Liu
3
Weijian Jiang
3*- 1 Department of Neurosurgery, Peking University People's Hospital, Beijing, Beijing Municipality, China
- 2 Qingdao Women and Children's Hospital, Qingdao, Shandong Province, China
- 3 Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China, Beijing, China
Carotid artery stenosis, primarily caused by atherosclerosis, is a major risk factor for ischemic stroke. Carotid endarterectomy (CEA) and carotid artery stenting (CAS) are established interventions to reduce stroke risk and restore cerebral blood flow. However, the effect of these treatments on circadian rhythms, and their influence on stroke recovery, remains underexplored. This study aims to assess how disruptions in circadian rhythms-specifically sleep quality and blood pressure variability-impact recovery in patients undergoing CEA or CAS..We conducted a prospective study involving 177 patients with carotid artery stenosis, all treated with either CEA or CAS. Patients were followed for 90 days post-treatment, with neurological outcomes evaluated using the NIHSS Stroke Scale (NIHSS). Circadian rhythm-related factors, including sleep quality (Pittsburgh Sleep Quality Index [PSQI]) and blood pressure variability (daytime systolic and nighttime diastolic BP), were assessed pre-and post-treatment. Stepwise regression was used to identify predictors of stroke recovery.
Keywords: Carotid artery stenosis, circadian rhythms, Carotid endarterectomy (CEA), Carotid artery stenting (CAS), PSQI (Pittsburgh Sleep Quality Index), NIHSS(National Institutes of Health Stroke Scale), IPAQ (International Physical Activity Questionnaire)
Received: 24 Sep 2024; Accepted: 02 Dec 2024.
Copyright: © 2024 Quan, Wang, Zhang, Sui, Zhang, Ji, Liu and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yi Quan, Department of Neurosurgery, Peking University People's Hospital, Beijing, 100044, Beijing Municipality, China
Weijian Jiang, Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing 100088, China, Beijing, China
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