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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Headache and Neurogenic Pain
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1500918

Short-term efficacy of right-to-left shunt closure in patients with vestibular migraine

Provisionally accepted
Yilin Lang Yilin Lang Sai Zhang Sai Zhang *Peifan Xie Peifan Xie *Yang Wang Yang Wang *Chuangwei Wang Chuangwei Wang *Wenting Wang Wenting Wang *Xien Zhu Xien Zhu *Ping Gu Ping Gu *
  • The First hospital of Hebei Medical University, Shijiazhuang, China

The final, formatted version of the article will be published soon.

    Objective: This study aims to evaluate the short-term efficacy of right-to-left shunt closure in vestibular migraine patients, and compare the efficacy between patent foramen ovale (PFO) closure and pulmonary arteriovenous malformation (PAVM) embolization. Additionally, the study identifies factors related to surgical outcomes.Methods: Forty-one patients with vestibular migraine and medium to large right-to-left shunts underwent surgery: PFO closure, PAVM embolization, or both. Baseline data and postoperative outcomes at one month, including migraine and dizziness frequency, duration, VAS, HIT-6, migraine scores, and DHI scores, were analyzed.. The correlation between efficacy and baseline data was analyzed.Results: At one month postoperatively, the frequency and duration of dizziness and migraine attacks significantly decreased, and the VAS, HIT-6, migraine scores, and DHI scores all significantly dropped (P < 0.001). There was no significant difference in the improvement rates of VAS, HIT-6, migraine scores, and DHI scores between the PFO group and the PAVM group (P < 0.001). Red blood cell parameters positively correlated with the improvement rates of VAS, HIT-6, migraine scores, and DHI. This approach was more effective in male patients than in female patients (P < 0.05).Right-to-left shunt closure has a significant short-term effect on patients with vestibular migraine, regardless of the shunt location. Red blood cell parameters may serve as predictive indicators for the surgical efficacy in these patients.

    Keywords: vestibular migraine, right-to-left shunt closure, efficacy, patent foramen ovale, Pulmonary arteriovenous malformation

    Received: 24 Sep 2024; Accepted: 28 Nov 2024.

    Copyright: © 2024 Lang, Zhang, Xie, Wang, Wang, Wang, Zhu and Gu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Sai Zhang, The First hospital of Hebei Medical University, Shijiazhuang, China
    Peifan Xie, The First hospital of Hebei Medical University, Shijiazhuang, China
    Yang Wang, The First hospital of Hebei Medical University, Shijiazhuang, China
    Chuangwei Wang, The First hospital of Hebei Medical University, Shijiazhuang, China
    Wenting Wang, The First hospital of Hebei Medical University, Shijiazhuang, China
    Xien Zhu, The First hospital of Hebei Medical University, Shijiazhuang, China
    Ping Gu, The First hospital of Hebei Medical University, Shijiazhuang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.