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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Neurorehabilitation
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1466252
This article is part of the Research Topic Advanced Technology for Human Movement Rehabilitation and Enhancement View all 13 articles

The relationship between the functional status of Upper Extremity motor neurons and motor function and prognosis in stroke patients

Provisionally accepted
Li Xiaoyi Li Xiaoyi 1Shao Zhen Shao Zhen 2Li Zhi Li Zhi 1Wei Xiupan Wei Xiupan 1Zong LiJuan Zong LiJuan 1Wang Pei Wang Pei 1Zhou Ting Zhou Ting 1Wang Hongxing Wang Hongxing 1*
  • 1 Southeast University, Nanjing, China
  • 2 The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    This study investigates the correlation between neuroelectrop-hysiological assessments such as motor unit number estimation (MUNE) and F-waves with upper extremity motor function and one-year prognosis in stroke patients.: Neuroelectrophysiological assessments of the abductor pollicis brevis muscle, including MUNE and F-waves, were conducted. Upper extremity motor function was evaluated using the Fugl-Meyer Assessment of Upper Extremity (FMA-UE) and the Modified Ashworth Scale (MAS). Pearson correlation and multiple linear regression analyses were performed to explore the relationship between upper extremity motor function and variables such as MUNE and F-waves. ROC curve analysis assessed the predictive ability of MUNE and F-waves for upper extremity motor function, and binary logistic regression analysis examined factors related to motor function improvement one year postdischarge. Results: A total of 130 patients were ultimately included. Significant differences in MUNE and occupancy rate of non-repeater F-waves (non-ORF) were found between hemiplegic and unaffected sides (P<0.001), with a significant difference in F-wave mean latency (P<0.05). Pearson correlation analysis showed a positive correlation between FMA-UE at admission and hemiplegic side's MUNE and non-ORF (P<0.001). Multiple linear regression indicated that hemiplegic side's MUNE (β=0.88, P<0.001) and non-ORF (β=0.275, P=0.005) influenced FMA-UE. ROC analysis demonstrated higher predictive ability for hemiplegic side's MUNE (AUC=0.696, P<0.001) than non-ORF (AUC=0.622, P=0.018). Binary logistic regression showed that hemiplegic side's MUNE was associated with FMA-UE improvement one year post-discharge.: MUNE and F-waves are correlated with upper extremity motor function in patients, reflecting their motor function status. These indicators have good predictive value for motor function and are associated with the prognosis of upper extremity motor function to a certain extent.

    Keywords: Stroke, Motor Neurons, repeater F-waves, MUNE, upper extremity motor function

    Received: 17 Jul 2024; Accepted: 10 Sep 2024.

    Copyright: © 2024 Xiaoyi, Zhen, Zhi, Xiupan, LiJuan, Pei, Ting and Hongxing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wang Hongxing, Southeast University, Nanjing, China

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