AUTHOR=Tang Zhuxiao , Wang Ming , Xiong Tao , Liu Weixian , Sun Hu , Ma Jiangchun 

TITLE=A case of spontaneous bilateral epidural hematoma associated with decreased coagulation factor XII activity: case report and literature review

JOURNAL=Frontiers in Neurology

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1460073

DOI=10.3389/fneur.2024.1460073

ISSN=1664-2295

ABSTRACT=<p>Epidural hematoma typically manifests following craniocerebral trauma, stemming from injury to the meningeal artery or venous system, predominantly on one side. Instances of spontaneous epidural hematoma are uncommon, with occurrences of spontaneous bilateral epidural hematoma being exceedingly rare. Sickle cell disease, adjacent paranasal sinusitis, and tumor metastases are the most prevalent causes of spontaneous epidural hematoma. This case study presents an individual with abdominal liposarcoma exhibiting reduced coagulation factor XII activity, who experienced sudden unconsciousness due to spontaneous acute bilateral epidural hematoma, and subsequently achieved a favorable outcome following surgical intervention.</p>