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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Experimental Therapeutics
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1453598
This article is part of the Research Topic Data Driven Analytics in Orofacial Pain View all articles

The Efficacy of Ultrasound-guided Pulsed Radiofrequency in the Treatment of Primary Glossopharyngeal Neuralgia

Provisionally accepted
Fubo LI Fubo LI HongCheng Lu HongCheng Lu *Gege Gong Gege Gong *Cehua Ou Cehua Ou *Yue Zhang Yue Zhang *
  • The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China

The final, formatted version of the article will be published soon.

    Objective: This study evaluates the clinical efficacy and safety of ultrasound-guided long duration, high voltage pulse radiofrequency (PRF) in managing primary glossopharyngeal neuralgia (GPN).Methods: Clinical data were retrospectively analyzed for 13 patients with primary GPN who underwent this treatment between August 2019 and October 2022. Visual Analog Scale (VAS) scores were assessed pre-treatment and at 1 week, 1 month, 3 months, and 6 months post-treatment.Additionally, the rates of discontinuation of oral oxcarbazepine and pregabalin, efficacy, and complication rates at 6 months post-procedure were monitored.Results: Significant post-treatment pain relief, was observed across all patients, with statistically significant improvements in VAS scores ( P <0.05). Discontinuation rates for oxcarbazepine and pregabalin were also high ( P <0.05). At the 6-month follow-up, 69.23% of patients achieved excellent and good efficacy, 84.61% demonstrated overall effectiveness, while 15.38% showed poor efficacy. No critical complications were reported in any case.Ultrasound-guided, long-term, high-voltage PRF effectively relieves primary glossopharyngeal neuralgia and improves quality of life. Featuring ease of operation, high safety and minimal complications making it a promising approach for clinical application.

    Keywords: Glossopharyngeal neuralgia (GPN), Pulsed radiofrequency (PRF), Ultrasound-guided, Effica cy, pregabalin, oxcarbazepine

    Received: 23 Jun 2024; Accepted: 14 Nov 2024.

    Copyright: © 2024 LI, Lu, Gong, Ou and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    HongCheng Lu, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China
    Gege Gong, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China
    Cehua Ou, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China
    Yue Zhang, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.