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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Neuro-Otology
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1449261
This article is part of the Research Topic Meniere’s Disease: From Diagnosis to Treatment View all articles

The dissociation between pathological caloric testing and a normal video head impulse test helps differentiate between Menière's disease, vestibular migraine, and other vestibular disordersa confirmatory study in a large cohort of 2101 patients

Provisionally accepted
Vergil Mavrodiev Vergil Mavrodiev 1,2*Michael Strupp Michael Strupp 1,2Anne-Sophie Vinck Anne-Sophie Vinck 3Raymond Van De Berg Raymond Van De Berg 4Louisa Lehner Louisa Lehner 1,2
  • 1 Ludwig Maximilian University of Munich, Munich, Germany
  • 2 German Center for Vertigo and Balance Disorders, Faculty of Medicine, Ludwig Maximilian University of Munich, Munich, Bavaria, Germany
  • 3 AZ Sint-Jan Brugge-Oostende AV, Brugge, West Flanders, Belgium
  • 4 Maastricht University Medical Centre, Maastricht, Limburg, Netherlands

The final, formatted version of the article will be published soon.

    Vestibular migraine (VM) and Menière's disease (MD) are characterized by episodes of vertigo of similar duration. It is well known that the differentiation between both diseases is not always possible based only on the patient history, physical examination and audiological testing. In addition, the quantification of the vestibular function can also be helpful since, among patients with MD, there is often a dissociation between a normal/pseudo-normal video head impulse test (vHIT) and reduced caloric testing. The goal of this confirmatory study was to determine the sensitivity, specificity, and positive and negative predictive values (PPV and NPV) of this dissociation to differentiate between MD and VM as well as between MD and other vestibular diseases.We performed a retrospective analysis of 2101 patients. The examination group consisted of 1100 patients; 627 (57%) with MD according to the diagnostic criteria of the Bárány Society and 423473 (43%) with VM. The comparison group consisted of 1001 patients with other peripheral, central, or functional vestibular disorders.Statistical analysis revealed for the dissociation the following findings:

    Keywords: Vertigo, Menière's disease, vestibular migraine, Video head impulse test, caloric testing, retrospective analysis, dissociation

    Received: 14 Jun 2024; Accepted: 29 Jul 2024.

    Copyright: © 2024 Mavrodiev, Strupp, Vinck, Van De Berg and Lehner. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Vergil Mavrodiev, Ludwig Maximilian University of Munich, Munich, Germany

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.