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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Epilepsy
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1448596

A Population-Based Analysis of the Global Burden of Epilepsy Across All Age Groups (1990-2021): Utilizing the Global Burden of Disease (GBD) 2021 Data

Provisionally accepted
Chenqi Zhang Chenqi Zhang 1*Yi Guo Yi Guo 2Zhiqiang Wang Zhiqiang Wang 1Kexin Zheng Kexin Zheng 1Lingzhi Yang Lingzhi Yang 1
  • 1 Chengdu BOE Hospital, Chengdu, China
  • 2 Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    To investigate the trends in epilepsy prevalence, incidence, mortality, and disabilityadjusted life-years (DALYs) in all ages, with risk factors for epilepsy -associated death, from 1990 to 2021.Using the standardized Global Burden of Disease (GBD) methodologies, we evaluated the burden of epilepsy in 204 countries and regions from 1990 to 2021, aiming to derive a more precise representation of the health burden posed by epilepsy by considering four distinct types of epidemiological data, namely the prevalence, incidence, mortality, and DALYs. The presented data were meticulously estimated and displayed both as numerical counts and as age-standardized rates per 100,000 persons of the population. All estimates were calculated with 95% uncertainty intervals (UI).

    Keywords: Epilepsy, Global burden of disease, Socioeconomic disparity, time trend, Prevalence, Incidence, Mortality, DALYs

    Received: 12 Aug 2024; Accepted: 06 Nov 2024.

    Copyright: © 2024 Zhang, Guo, Wang, Zheng and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Chenqi Zhang, Chengdu BOE Hospital, Chengdu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.