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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1402626
This article is part of the Research Topic Update in Endoscopic and Transcranial Approaches for Skull Base Meningiomas View all 8 articles

Incidence and influencing factors of Olfactory Dysfunction in patients one week after Endoscopic Transsphenoidal Resection of pituitary tumor: A cross-sectional study of 158 Patients

Provisionally accepted
Mei S. Zhou Mei S. Zhou Zhi Zeng Zhi Zeng *Min Chen Min Chen Bo L. Zou Bo L. Zou Rong S. Shao Rong S. Shao
  • People’s Hospital of Deyang City, Deyang, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Objective To investigate the current situation of olfactory dysfunction in patients after endoscopic transsphenoidal resection of pituitary tumors, and analyze its influencing factors, to provide references for clinical nursing and rehabilitation. Methods A cross-sectional study design and convenience sampling method were used to investigate 158 patients with pituitary tumors treated by endoscopic transsphenoidal pituitary tumor resection in the Department of Neurosurgery of three Grade-A general hospitals in Sichuan Province from January 2022 and June 2023. The olfactory function of patients was evaluated one week after surgery, and the general clinical data and olfactory related data of patients were collected, and the influencing factors of olfactory disorder were analyzed by logistic regression. Results The incidence of olfactory dysfunction was 73.42%. analysis revealed that the formation of blood scabs, nasal cavity adhesion, cerebrospinal fluid leakage and operation time were independent risk factors for olfactory dysfunction in patients after transsphenoidal pituitary tumor resection (P<0.05). Conclusion The incidence of olfactory dysfunction is high in patients after endoscopic transsphenoidal resection of pituitary tumors, suggesting that medical staff should pay close attention to and identify patients with olfactory dysfunction based on the guidance of disease knowledge and skills, develop targeted nursing interventions, and promote the improvement of patients' olfactory function and quality of life.

    Keywords: pituitary tumor, endoscopic transsphenoidal resection, Postoperative olfactory dysfunction, endoscope, Influence factor

    Received: 18 Mar 2024; Accepted: 28 Jun 2024.

    Copyright: © 2024 Zhou, Zeng, Chen, Zou and Shao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhi Zeng, People’s Hospital of Deyang City, Deyang, Sichuan Province, China

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