AUTHOR=Qin Feng , Guo Siquan , Yin Xiuwen , Lu Xiaoyu , Ma Jing 

TITLE=Auditory and speech outcomes of cochlear implantation in patients with Waardenburg syndrome: a meta-analysis

JOURNAL=Frontiers in Neurology

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1372736

DOI=10.3389/fneur.2024.1372736

ISSN=1664-2295

ABSTRACT=<sec id="sec1"><title>Objective</title><p>This study aims to assess the potential efficacy of cochlear implantation as a treatment for patients with Waardenburg syndrome (WS) and to guide clinical work by comparing the effect of auditory and speech recovery after cochlear implantation in patients with WS and non-WS.</p></sec><sec id="sec2"><title>Methods</title><p>PubMed, the Cochrane Library, CNKI, and Wanfang Data were sources for retrieving literature on cochlear implantation in WS, and clinical data meeting the inclusion criteria were meta-analyzed using RevMan5.41.</p></sec><sec id="sec3"><title>Results</title><p>A total of nine articles were included in this study, including 132 patients with WS and 815 patients in the control group. Meta-analysis showed that there are no significant differences in the scores for categories of audit performance (CAP), speech intelligibility rating (SIR), and parents’ evaluation of aural/oral performance of children (PEACH) between the WS group and the control group.</p></sec><sec id="sec4"><title>Conclusion</title><p>Cochlear implantation demonstrates comparable auditory and speech recovery outcomes for WS patients and non-WS patients.</p></sec>