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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Neurogenetics
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1371375

Frontier and Hotspot Evolution in Cerebrotendinous Xanthomatosis: a Bibliometric analysis from 1993 to 2023

Provisionally accepted
Fei Luo Fei Luo 1Yali Ding Yali Ding 1,2Shanyun Zhang Shanyun Zhang 3Juanjuan Diao Juanjuan Diao 4Bin Yuan Bin Yuan 5*
  • 1 Nanjing University of Chinese Medicine, Nanjing, China
  • 2 Nanjing Gaochun Traditional Chinese Medicine Hospital, Nanjing, China
  • 3 Haining Hospital of Chinese Medicine, Haining, China
  • 4 Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
  • 5 Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China

The final, formatted version of the article will be published soon.

    Background: Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disease associated with lipid metabolic disorders.Because of its clinical diversity and rarity, the diagnosis is often unclear.However, there is still a lack of reports on bibliometric analysis of CTX.The aim of this study was to assess the progress and research developments of CTX over the past three decades, identify emerging trends, and establish novel directions for future research. Methods: The eligible literature were screened from the Web of Science Core Collection (WoSCC) database. The annual publication, countries, institutions, authors, journals, keywords and references were visually analyzed by Microsoft Excel 2019, CiteSpace 6.2.R4, VOSviewer 1.6.18 and online bibliometrics website (https://bibliometric.com/). Results: A total of 561 publications from WoSCC were included in this study. The United States is the country with the largest number of publications, and Karolinska Institutet is the institution with the largest number of publications. Bjorkhem I ranks as the most published and cited author in the last three decades. Journal of Lipid Research is the most widely published and cited journal. The strongest burst of keywords is "diagnosis".Unraveling the pathogenesis of CTX and improving its diagnosis and treatment continue to be critical challenges that require urgent attention. Future research endeavors will be centered on enhancing the efficiency and accuracy of early diagnosis and intervention.

    Keywords: bibliometric analysis, Cerebrotendinous xanthomatosis, Citespace, VOSviewer, Web of Science

    Received: 17 Jan 2024; Accepted: 15 Jul 2024.

    Copyright: © 2024 Luo, Ding, Zhang, Diao and Yuan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Bin Yuan, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.