AUTHOR=Zhao Li , Guo Yiping , Zhou Xuelei , Mao Wei , Zhu Hongyu , Chen Linlin , Liu Xianchun , Zhang Longyi , Xie Ying , Li Linji TITLE=The research progress of perioperative non-pharmacological interventions on postoperative cognitive dysfunction: a narrative review JOURNAL=Frontiers in Neurology VOLUME=15 YEAR=2024 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1369821 DOI=10.3389/fneur.2024.1369821 ISSN=1664-2295 ABSTRACT=

Postoperative cognitive dysfunction (POCD) is a common neurological complication in elderly patients after surgery and general anesthesia. The occurrence of POCD seriously affects the postoperative recovery of patients, and leads to prolonged hospital stay, reduced quality of life, increased medical costs, and even higher mortality. There is no definite and effective drug treatment for POCD. More evidence shows that perioperative non-pharmacological intervention can improve postoperative cognitive function and reduce the incidence of POCD. Therefore, our studies summarize the current non-pharmacological interventions of POCD from the aspects of cognitive training, physical activity, transcutaneous electrical acupoint stimulation, noninvasive brain stimulation, non-pharmacological sleep improvement, music therapy, environment, and multimodal combination Interventions, to provide more data for clinical application and research.