AUTHOR=Park Soo-Hyun , Jang Soo-Im , Lee Eun-Ja , Kim Nam-Hee 

TITLE=Case report: Tolosa-Hunt syndrome—expanding the neuromyelitis optica spectrum disorder phenotype?

JOURNAL=Frontiers in Neurology

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1326867

DOI=10.3389/fneur.2024.1326867

ISSN=1664-2295

ABSTRACT=<p>Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune astrocytopathy caused by the autoantibody of aquaporin-4 (AQP4). Herein, we report a case of Tolosa-Hunt syndrome presenting with abducens palsy and AQP4 antibodies. This was a rare case of AQP4-immunoglobulin G seropositivity in a patient with Tolosa-Hunt syndrome. Our findings may expand the clinical phenotype of NMOSD and indicate that clinicians should consider testing for AQP4 antibodies in patients with Tolosa-Hunt syndrome.</p>