AUTHOR=Akpınar Çetin Kürşad , Gurkas Erdem , Ozdemir Atilla Ozcan , Doğan Hasan , Önalan Ayşenur , Yıldırım Serhan , Memiş Zülfikar , Aytaç Emrah , Acar Bilgehan Atılgan , Öğün Muhammed Nur , Aykaç Özlem , Uysal Kocabaş Zehra , Acar Türkan , Eryılmaz Halil Alper , Topaktaş Berkhan TITLE=Three years’ interventional neurology experience in Turkey with the Thrombite thrombectomy device in large vessel occlusion in the anterior circulation: safety, efficacy, and clinical outcome JOURNAL=Frontiers in Neurology VOLUME=15 YEAR=2024 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1320510 DOI=10.3389/fneur.2024.1320510 ISSN=1664-2295 ABSTRACT=Introduction

While the Thrombite device differs from the Solitare stent with its Helical open-side structure feature, it shows great similarity with its other features. We assessed the Thrombite device’s effectiveness and safety in this study.

Materials and methods

The study was a retrospective analysis of patients who were included in the Turkish Interventional Neurology database and who had mechanical thrombectomy with the Thrombite device as the first choice between January 2020 and January 2023. The type of study is descriptive research.

Result

Using the Thrombite thrombectomy device, 525 patients received treatment. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 13, the median initial Alberta Stroke Program Early Computed Tomography (ASPECT) score was 8, and the mean patient age was 68.6+11.7 years. Between the groin puncture and the successful recanalization, the median time was 34 minutes (interquartile range [IQR]: 15–45). 48.2% (modified treatment in cerebral infarction; mTICI) 2b/3% and 33.9% (mTICI 2c/3) were the first-pass recanalization rates. In the end, 87.7% of patients had effective recanalization (thrombolysis in cerebral infarction 2b/3). In the “first-pass” subgroup, the favorable functional result (modified Rankin Scale 0–2) was 51.8%, while it was 41.6% for the entire patient population. The rate of embolization into new territory/different territory were 2.1/0.1%. 23 patients (4.5%) had symptomatic hemorrhage.

Conclusion

The Thrombite device showed a good safety profile and high overall successful recanalization rates in our experience.