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CASE REPORT article

Front. Neurol.
Sec. Sleep Disorders
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1293695
This article is part of the Research Topic Case Reports in Sleep Disorders : volume III - 2023 View all 6 articles

Symptoms similar to Kleine-Levin syndrom in a patient with basilar artery occlusion: A case report and literature review

Provisionally accepted
Linghua Kong Linghua Kong 1*Chunyan Li Chunyan Li 2
  • 1 Department of Neurology, Binzhou Central Hospital, Binzhou, China
  • 2 Department of Neurology, Binzhou Central Hospital, Binzhou, Shandong Province, China

The final, formatted version of the article will be published soon.

    Introduction: Kleine-Levin syndrome (KLS) is a rare disorder characterized by recurrent periodic hypersomnia, cognitive disturbances, hyperphagia, and hypersexuality. Although many factors have been associated with its occurrence, little is known about treatment. Herein, we present a case of symptoms similar to KLS thought to be related to vascular occlusion disease. Case Description: An 81-year-old woman was admitted to the hospital due to recurring episodes of disturbance of consciousness, cognitive disorder, and hyperphagia for 18 years. She was diagnosed with KLS and basilar artery occlusion. Endovascular and antithrombotic therapy was initiated, and her symptoms fully resolved within 2 weeks of treatment initiation. Conclusion: KLS has diverse clinical presentations and demonstrates variable therapeutic responses. Vascular disease or blood flow disorder may be one possible factor for this disease. This case underscores the need for further research into the etiology and pathogenesis of KLS to promote evidencebased approaches for its diagnosis and treatment.

    Keywords: Kleine-Levin Syndrome, Hypersomnia, Pathogenesis, vascular disease, Thrombectomy

    Received: 13 Sep 2023; Accepted: 29 Jul 2024.

    Copyright: © 2024 Kong and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Linghua Kong, Department of Neurology, Binzhou Central Hospital, Binzhou, China

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