AUTHOR=Austen William G. , Remy Katya , Packowski Kathryn , Hazewinkel Merel H. J. , Gfrerer Lisa , Mathew Paul G. TITLE=Refractory occipital neuralgia treatment with nerve decompression surgery: a case series JOURNAL=Frontiers in Neurology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1284101 DOI=10.3389/fneur.2023.1284101 ISSN=1664-2295 ABSTRACT=Background

The management of refractory occipital neuralgia (ON) can be challenging. Selection criteria for occipital nerve decompression surgery are not well defined in terms of clinical features and best preoperative medical management.

Methods

In total, 15 patients diagnosed with ON by a board-certified, fellowship-trained headache specialist and referred to a plastic surgeon for nerve decompression surgery were prospectively enrolled. All subjects received trials of occipital nerve blocks (NB), at least three preventive medications, and onabotulinum toxin (BTX) prior to surgery before referral to a plastic surgeon. Treatment outcomes included headache frequency (headache days/month), intensity (0–10), duration (h), and response to medication/injectable therapies at 12 months postoperatively.

Results

Preoperatively, median headache days/month was 30 (20–30), intensity 8 (8–10), and duration 24 h (12–24). Patients trialed 10 (±5.8) NB and 11.7 (±9) BTX cycles. Postoperatively, headache frequency was 5 (0–16) days/month (p < 0.01), intensity was 4 (0–6) (p < 0.01), and duration was 10 (0–24) h (p < 0.01). Median patient-reported percent resolution of ON headaches was 80% (70–85%). All patients reported improvement of comorbid headache disorders, most commonly migraine, and a reduction, discontinuation, or increased effectiveness of medications, NB and BTX.

Conclusion

All patients who underwent treatment for refractory ON by a headache specialist and plastic surgeon benefited from nerve decompression surgery in various degrees. The collaborative selection criteria employed in this study may be replicable in clinical practice.