AUTHOR=Wang Ce , Cai Zehao , Huang Yue , Liu Xinrui , Liu Xing , Chen Feng , Li Wenbin TITLE=Honokiol in glioblastoma recurrence: a case report JOURNAL=Frontiers in Neurology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1172860 DOI=10.3389/fneur.2023.1172860 ISSN=1664-2295 ABSTRACT=

Glioblastoma is the most common and aggressive primary tumor in the central nervous system. There is no standard of care for patients with recurrent GBM. Honokiol is a pleiotropic lignan and has the potential to be a potent and safe anticancer agent in human GBM when it is encapsulated by liposomes. We report an efficient and safe response to three phases of treatment with liposomal honokiol in a patient with recurrent glioblastoma.