AUTHOR=Jiang Xinzhao , Shi Zongjie , Wang Peng , Wang Xu , Liu Fang 

TITLE=Branch-site occlusion sign predicts the embolic origin of acute ischemic stroke: a meta-analysis

JOURNAL=Frontiers in Neurology

VOLUME=14

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1139756

DOI=10.3389/fneur.2023.1139756

ISSN=1664-2295

ABSTRACT=<sec><title>Objective</title><p>The study aimed to investigate whether branch-site occlusion (BSO) sign could predict the etiology of acute intracranial large artery occlusion (ILVO) and the stentriever (SR) response.</p></sec><sec><title>Methods</title><p>We systematically reviewed studies that evaluated the predictive role of BSO for the etiology of ILVO-AIS or EVT outcome between 1 January 2000 and 31 August 2022 from PubMed, Embase, and Web of Science.</p></sec><sec><title>Results</title><p>The sensitivity and specificity of BSO sign predicting etiology of ILVO-AIS were 0.87 (95% CI 0.81–0.91) and 0.64 (95% CI 0.33–0.87), respectively. The sensitivity and specificity of BSO sign predicting stentriever response were 0.84 (95% CI 0.63–0.94) and 0.61 (95% CI 0.18–0.92), respectively.</p></sec><sec><title>Conclusion</title><p>The BSO sign could be a valid and precise imaging marker to predict embolism caused ILVO-AIS and recanalization success by SR without rescue therapy.</p></sec>