AUTHOR=Mu Jie-Dan , Ma Liang-Xiao , Zhang Zhou , Qian Xu , Zhang Qin-Yong , Ma Ling-Hui , Sun Tian-Yi 

TITLE=The factors affecting neurogenesis after stroke and the role of acupuncture

JOURNAL=Frontiers in Neurology

VOLUME=14

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1082625

DOI=10.3389/fneur.2023.1082625

ISSN=1664-2295

ABSTRACT=<p>Stroke induces a state of neuroplasticity in the central nervous system, which can lead to neurogenesis phenomena such as axonal growth and synapse formation, thus affecting stroke outcomes. The brain has a limited ability to repair ischemic damage and requires a favorable microenvironment. Acupuncture is considered a feasible and effective neural regulation strategy to improve functional recovery following stroke <italic>via</italic> the benign modulation of neuroplasticity. Therefore, we summarized the current research progress on the key factors and signaling pathways affecting neurogenesis, and we also briefly reviewed the research progress of acupuncture to improve functional recovery after stroke by promoting neurogenesis. This study aims to provide new therapeutic perspectives and strategies for the recovery of motor function after stroke based on neurogenesis.</p>