AUTHOR=Zhou Tengfei , Li Tianxiao , Zhu Liangfu , Li Zhaoshuo , Li Qiang , Wang Ziliang , Wu Liheng , He Yingkun , Li Yucheng , Zhou Zhilong , Guan Min , Ma Zhenkai , pei Xiaoxi , Meng Shuhui , Feng Yingpu , Zhang Guifang , Zhao Wenli , Liu Xiao , Wang Meiyun TITLE=One-stop stroke management platform reduces workflow times in patients receiving mechanical thrombectomy JOURNAL=Frontiers in Neurology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1044347 DOI=10.3389/fneur.2022.1044347 ISSN=1664-2295 ABSTRACT=Background and purpose

Clinical outcome in patients who received thrombectomy treatment is time-dependent. The purpose of this study was to evaluate the efficacy of the one-stop stroke management (OSSM) platform in reducing in-hospital workflow times in patients receiving thrombectomy compared with the traditional model.

Methods

The data of patients who received thrombectomy treatment through the OSSM platform and traditional protocol transshipment pathway were retrospectively analyzed and compared. The treatment-related time interval and the clinical outcome of the two groups were also assessed and compared. The primary efficacy endpoint was the time from door to groin puncture (DPT).

Results

There were 196 patients in the OSSM group and 210 patients in the control group, in which they were treated by the traditional approach. The mean DPT was significantly shorter in the OSSM group than in the control group (76 vs. 122 min; P < 0.001). The percentages of good clinical outcomes at the 90-day time point of the two groups were comparable (P = 0.110). A total of 121 patients in the OSSM group and 124 patients in the control group arrived at the hospital within 360 min from symptom onset. The mean DPT and time from symptom onset to recanalization (ORT) were significantly shorter in the OSSM group than in the control group. Finally, a higher rate of good functional outcomes was achieved in the OSSM group than in the control group (53.71 vs. 40.32%; P = 0.036).

Conclusion

Compared to the traditional transfer model, the OSSM transfer model significantly reduced the in-hospital delay in patients with acute stroke receiving thrombectomy treatment. This novel model significantly improved the clinical outcomes of patients presenting within the first 6 h after symptom onset.