AUTHOR=Dubinski Daniel , Won Sae-Yeon , Trnovec Svorad , Gounko Kseniya , Baumgarten Peter , Warnke Philipp , Cantré Daniel , Behmanesh Bedjan , Bernstock Joshua D. , Freiman Thomas M. , Gessler Florian , Sola Steffen 

TITLE=Recurrence of chronic subdural hematoma due to low-grade infection

JOURNAL=Frontiers in Neurology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1012255

DOI=10.3389/fneur.2022.1012255

ISSN=1664-2295

ABSTRACT=<p>Despite the high incidence and multitudes of operative techniques, the risk factors for chronic subdural hematoma (CSDH) recurrence are still under debate and a universal consensus on the pathophysiology is lacking. We hypothesized that clinically inapparent, a low-grade infection could be responsible for CSDH recurrence. This investigation is a single-center prospective observational study including patients with recurrent CSDH. In total, 44 patients with CSDH recurrence received an intraoperative swab-based microbiological test. The intraoperative swab revealed an inapparent low-grade hematoma infection in 29% of the recurrent CSDH cases. The majority (69%) of the identified germs belonged to the <italic>staphylococcus</italic> genus. We therefore, propose a novel potential pathophysiology for CSDH recurrence.</p>