AUTHOR=Wu Xuan , Duan Zuowei , Liu Yihui , Zhou Changwu , Jiao Zhiyun , Zhao Yi , Tang Tieyu 

TITLE=Incidental Unruptured Intracranial Aneurysms Do Not Impact Outcome in Patients With Acute Cerebral Infarction

JOURNAL=Frontiers in Neurology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.613027

DOI=10.3389/fneur.2021.613027

ISSN=1664-2295

ABSTRACT=<p><bold>Background:</bold> This study was to examine the patients with acute cerebral infarction (ACI) treated at a single center over 9 years and who underwent Unruptured intracranial aneurysm (UIA) screening by three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA), and to explore the factors associated with outcomes.</p><p><bold>Methods:</bold> The outcome was the modified Rankin scale (mRS) score at 90 days after stroke onset. The outcome was classified into a good outcome (mRS score of 0–2 points) and poor outcome (mRS score of 3–6 points).</p><p><bold>Results:</bold> UIAs were found in 260 (6.5%) of 4,033 patients with ACI; 2,543 (63.1%) had a good outcome, and 1,490 (36.9%) had a poor outcome. There was no difference in outcomes between the two groups (<italic>P</italic> = 0.785). The multivariable analysis showed that age (OR = 1.009, 95%CI: 1.003–1.014, <italic>P</italic> = 0.003), diabetes (OR = 1.179, 95%CI: 1.035–1.342, <italic>P</italic> = 0.013), ischemic stroke history (OR = 1.451, 95%CI: 1.256–1.677, <italic>P</italic> &lt; 0.001), and baseline NIHSS score (OR = 1.034, 95%CI: 1.018–1.050, <italic>P</italic> &lt; 0.001) were independently associated with the 90-day outcomes in patients with ACI. The presence of incidental UIA was not associated with outcomes after ACI.</p><p><bold>Conclusions:</bold> Age, diabetes, ischemic stroke history, and baseline NIHSS score were independently associated with the early outcomes of patients with ACI.</p>