AUTHOR=Charbonnier Guillaume , Desilles Jean-Philippe , Escalard Simon , Maier Benjamin , Ciccio Gabriele , Smajda Stanislas , Fahed Robert , Delvoye François , Redjem Hocine , Blanc Raphaël , Piotin Michel , Mazighi Mikael 

TITLE=Timing and Spectrum of Neurological Complications After Flow Diverter Implantation for Intracranial Aneurysms

JOURNAL=Frontiers in Neurology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.590383

DOI=10.3389/fneur.2021.590383

ISSN=1664-2295

ABSTRACT=<p><bold>Background and Purpose:</bold> The aim of this study was to characterize neurological complications after flow diverter (FD) treatment on a long follow-up cohort and identify predictive factors associated with these complications.</p><p><bold>Methods:</bold> This study was conducted on a monocentric cohort of patients treated for intracranial aneurysms by FD.</p><p><bold>Results:</bold> Between September 2008 and July 2018, 413 patients were treated for 514 aneurysms: 18% of the patients presented with at least one neurological complication during a median follow-up of 446 days (IQR 186–1,210). Sixty-one patients presented with ischemic complications, 13 with hemorrhagic ones and 10 with compressive processes. Among 89 neurological complications 64.5% were peri-operative (occurring within the 30 days following the procedure) and 35.5% were delayed after 1 month.</p><p><bold>Conclusions:</bold> Overall, neurological complications after FD implantation were overrepresented by cerebrovascular ischemic events occurring during the peri-operative period, but also in a delayed manner after 1 year. Long-term follow-up is relevant after aneurysm intervention using FD.</p>