AUTHOR=Woodhall Mark , Mitchell James W. , Gibbons Emily , Healy Sarah , Waters Patrick , Huda Saif 

TITLE=Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19

JOURNAL=Frontiers in Neurology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.598531

DOI=10.3389/fneur.2020.598531

ISSN=1664-2295

ABSTRACT=<p>A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was confirmed by nasopharyngeal swab and MOG-IgG serological reversion was noted. Visual function improved following steroids and plasma exchange. This case highlights a possible causal association between inflammation due to COVID-19 and a relapse of MOG-IgG associated disease. It also highlights the clinical relevance of reporting MOG-IgG titers in MOG-IgG associated disease.</p>