AUTHOR=Wan Hailin , Lu Gang , Huang Lei , Ge Liang , Jiang Yeqing , Li Gaohui , Leng Xiaochang , Xiang Jianping , Zhang Xiaolong 

TITLE=Hemodynamic Effect of the Last Finishing Coils in Packing the Aneurysm Neck

JOURNAL=Frontiers in Neurology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.598412

DOI=10.3389/fneur.2020.598412

ISSN=1664-2295

ABSTRACT=<p><bold>Background:</bold> Using the finishing coils to densely pack the aneurysm neck is necessary. However, the exact hemodynamic effect of finishing coils in packing the aneurysm neck is unknown.</p><p><bold>Objective:</bold> To evaluate the hemodynamic characteristics of finishing coils to densely pack the aneurysm neck, using finite element method simulation.</p><p><bold>Methods:</bold> A computational study was performed based on a 44-year-old female patient with an unruptured wide-necked carotid-ophthalmic artery aneurysm treated with low-profile visualized intraluminal support stent-assisted coil embolization. Four computational fluid dynamics models including pre-treatment, post-stenting, common stent-assisted coil embolization (SACE), and common SACE with finishing coils were evaluated qualitatively and quantitatively.</p><p><bold>Results:</bold> Compared with the baseline of pretreatment model (100%), sac-averaged velocity in post-stenting, common SACE, and common SACE with finishing coil models decreased to 95.68%, 24.38%, and 13.20%, respectively; high flow volume (&gt;0.1 m/s) around the aneurysm neck decreased to 92.19%, 9.59%, and 5.57%, respectively; and mean wall shear stress increased or decreased to 107%, 25.94%, and 23.89%, respectively.</p><p><bold>Conclusion:</bold> Finishing coils to densely pack the aneurysm neck can generate favorable hemodynamic modifications, which may decrease the recurrence.</p>