AUTHOR=Hanxin Kong , Xiaomin Wang , Hao Ying , Shuihong Zheng 

TITLE=Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis

JOURNAL=Frontiers in Neurology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.571382

DOI=10.3389/fneur.2020.571382

ISSN=1664-2295

ABSTRACT=<p><bold>Introduction:</bold> With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis.</p><p><bold>Case Report:</bold> We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low.</p><p><bold>Conclusion:</bold> This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis.</p>