AUTHOR=Wang Ran , Liu Nian , Tao Yun-Yun , Gong Xue-Qin , Zheng Jing , Yang Cui , Yang Lin , Zhang Xiao-Ming 

TITLE=The Application of rs-fMRI in Vascular Cognitive Impairment

JOURNAL=Frontiers in Neurology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.00951

DOI=10.3389/fneur.2020.00951

ISSN=1664-2295

ABSTRACT=<p>The incidence of vascular cognitive impairment (VCI) has been increasing for years and has become a major disabling factor in middle-aged and elderly populations. The pathogenesis of VCI is unclear, and there are no standard diagnostic criteria. Resting-state functional magnetic resonance imaging (rs-fMRI) can be used to detect spontaneous brain functional activity in a resting state, which facilitates in-depth investigation of the pathogenesis of VCI and provides an objective reference for early diagnosis, differential diagnosis, and prognostic evaluation. This article mainly reviews the principle and analysis of rs-fMRI data, as well as the progress of its application for VCI diagnosis.</p>