AUTHOR=Hassan Ameer E. , Rabah Rani R. , Preston Laurie , Tekle Wondwossen G. 

TITLE=STEPS-T Program Improves Endovascular Treatment Outcomes of Acute Ischemic Stroke; A 6-Year Study

JOURNAL=Frontiers in Neurology

VOLUME=10

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.01251

DOI=10.3389/fneur.2019.01251

ISSN=1664-2295

ABSTRACT=<p><bold>Background:</bold> Early endovascular recanalization of occluded vessels in acute ischemic stroke (AIS) is a major contributor to good clinical outcome. We report the analysis of all AIS patients throughout a 6-year experience following the deployment of a quality initiative aiming at improving care, speed and maintaining quality for AIS treatment.</p><p><bold>Methods:</bold> Using a prospectively collected endovascular database at a comprehensive stroke center between 2012 and 2017, workflow/outcomes were recorded. There were no exclusion criteria. During the first year, a quality program employing “digital-object” technology, staff education, and workflow improvement was implemented to reduce time-to-treatment. Using electronic recording, workflow times were collected for onset (T<sub>O</sub>), CT (T<sub>CT</sub>), door (T<sub>D</sub>), angiography-suite (T<sub>A</sub>), groin puncture (T<sub>G</sub>), DSA (T<sub>DSA</sub>), and recanalization (T<sub>R</sub>). Recanalization time (T<sub>G</sub>-T<sub>R</sub>) and workflow intervals were compared at Year 1 and 6.</p><p><bold>Results:</bold> Analysis of 382 patients (aged 71.3 ± 12.9) undergoing mechanical thrombectomy for AIS (206 male and 176 female) was performed. Recanalization time was significantly reduced from 82 min in 2012 to 34 min by 2017 (IQR 52–117 min and 23–49 min), a 59% reduction (<italic>P</italic> &lt; 0.001). Further, consistent year-over-year reductions in setup time (T<sub>A</sub>-T<sub>G</sub>) (44% improvement) and T<sub>CT</sub> to T<sub>A</sub> times were observed. During the same period, clinical outcome significantly improved year-over-year as measured with the modified Rankin Scale 0–2 (33, 37, 38, 41, 53, and 58%).</p><p><bold>Conclusions:</bold> Significant improvements were observed following the deployment of a quality initiative enabling iterative evidence-based process improvements, thereby sustaining significant reductions in time-to-treat and improved clinical outcomes for AIS patients.</p>