AUTHOR=Jin Yang , Sun Li Hua , Yang Wei , Cui Ran Ji , Xu Song Bai TITLE=The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders JOURNAL=Frontiers in Neurology VOLUME=10 YEAR=2019 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00515 DOI=10.3389/fneur.2019.00515 ISSN=1664-2295 ABSTRACT=

The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis. However, the potential mechanism of BDNF action in the neuroimmune axis' regulation of mood disorders remains unclear. Therefore, in this review, we focus on the recent progress of BDNF in influencing mood disorders, by participating in alterations of the neuroimmune axis. This may provide evidence for future studies in this field.