AUTHOR=Szczepańska Aleksandra , Dziadkowiak Edyta , Bladowska Joanna , Kipiński Lech , Budrewicz Sławomir , Koszewicz Magdalena 

TITLE=The Usefulness of Quantitative EEG and Advanced MR Techniques in the Monitoring and Long-Term Prognosis of Lance-Adams Syndrome

JOURNAL=Frontiers in Neurology

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00214

DOI=10.3389/fneur.2019.00214

ISSN=1664-2295

ABSTRACT=<p><bold>Objectives:</bold> Chronic post-hypoxic myoclonus, known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmonary resuscitation. It is characterized by intention myoclonus, cerebellar ataxia, and preserved intellect. The basis of the disease and its long-term prognosis remain unclear.</p><p><bold>Case report:</bold> The authors present a 53-year-old woman with a history of asthma bronchiale who suffered from myoclonus after hypoxic brain damage due to cardiac arrest. Advanced electrophysiological (quantitative EEG) and MR (MR spectroscopy) techniques were employed.</p><p><bold>Conclusions:</bold> Over long-term observation the results suggested permanent synaptic rearrangements of the neuronal networks due to brain plasticity in the patient after the brain hypoxia.</p>