AUTHOR=Zeng Yuzhe , Wang Nawen , Guo Tiantian , Zheng Qiuyang , Wang Shuang , Wu Songsong , Li Xi , Wu Jin , Chen Zhida , Xu Huaxi , Wang Xin , Lin Bin TITLE=Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation JOURNAL=Frontiers in Neurology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2018.01059 DOI=10.3389/fneur.2018.01059 ISSN=1664-2295 ABSTRACT=
Sorting nexin 27 (SNX27) is an endosome-associated cargo adaptor that is involved in various pathologies and development of neurological diseases. However, the role of SNX27 in spinal cord injury (SCI) remains unclear. In this study, we found that SNX27 was up-regulated in injured mice spinal cords by western blot and immunofluorescence. A comparative analysis of Basso mouse scale (BMS), footprint test and corticospinal tract (CST) tracing in