AUTHOR=Beeskow Anne B. , Oberstadt Moritz , Saur Dorothee , Hoffmann Karl-Titus , Lobsien Donald 

TITLE=Delayed Post-hypoxic Leukoencephalopathy (DPHL)—An Uncommon Variant of Hypoxic Brain Damage in Adults

JOURNAL=Frontiers in Neurology

VOLUME=9

YEAR=2018

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2018.00708

DOI=10.3389/fneur.2018.00708

ISSN=1664-2295

ABSTRACT=<p>Delayed post-hypoxic leukoencephalopathy (DPHL) is an uncommon, potentially under-recognized, cause of hypoxia induced white matter injury. It characteristically follows a biphasic course: After an initial phase of altered neurologic status a recovery occurs which is then followed by a recurring phase of neurologic deterioration, typically 2–4 weeks after the initial event. At this time white matter changes can be identified on MRI, which are the hallmark of DPHL. The characteristics and the typical MR-imaging signs of DPHL are discussed in this case report.</p>