AUTHOR=Salama Gayle R. , Heier Linda A. , Patel Praneil , Ramakrishna Rohan , Magge Rajiv , Tsiouris Apostolos John TITLE=Diffusion Weighted/Tensor Imaging, Functional MRI and Perfusion Weighted Imaging in Glioblastoma—Foundations and Future JOURNAL=Frontiers in Neurology VOLUME=8 YEAR=2018 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00660 DOI=10.3389/fneur.2017.00660 ISSN=1664-2295 ABSTRACT=

In this article, we review the basics of diffusion tensor imaging and functional MRI, their current utility in preoperative neurosurgical mapping, and their limitations. We also discuss potential future applications, including implementation of resting state functional MRI. We then discuss perfusion and diffusion-weighted imaging and their application in advanced neuro-oncologic practice. We explain how these modalities can be helpful in guiding surgical biopsies and differentiating recurrent tumor from treatment related changes.