AUTHOR=Sarkis Rani A. , Willment Kim C. , Gale Seth A. , Dworetzky Barbara A. 

TITLE=Recurrent Epileptic Auras As a Presenting Symptom of Alzheimer’s Disease

JOURNAL=Frontiers in Neurology

VOLUME=8

YEAR=2017

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00360

DOI=10.3389/fneur.2017.00360

ISSN=1664-2295

ABSTRACT=<p>Seizures are a common co-morbidity during the course of Alzheimer’s disease (AD) and in a subset of patients may be one of the presenting symptoms. In this case series, we highlight three patients with recurrent medically refractory epileptic auras whose work up ultimately lead to the diagnosis of AD. All three patients underwent prolonged EEG, serial neuropsychological testing, FDG-PET, cerebrospinal fluid (CSF) AD biomarkers, and MRI. CSF biomarkers were particularly helpful in two cases. These cases highlight the importance of having a high index of suspicion for AD in new onset “idiopathic” epilepsy in the elderly.</p>