AUTHOR=Giladi Nir , Mirelman Anat , Thaler Avner , Orr-Urtreger Avi TITLE=A Personalized Approach to Parkinson’s Disease Patients Based on Founder Mutation Analysis JOURNAL=Frontiers in Neurology VOLUME=7 YEAR=2016 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2016.00071 DOI=10.3389/fneur.2016.00071 ISSN=1664-2295 ABSTRACT=
While the phenotype of Parkinson disease (PD) is heterogeneous, treatment approaches are mostly uniform. Personalized medicine aims to treat diseases with targeted therapies based on cumulative variables, including genotype. We believe that sufficient evidence has accumulated to warrant the initiation of personalized medicine in PD based on subjects genotype and provide examples for our reasoning from observations of