AUTHOR=Grabau Olga , Leonhardi Jochen , Reimers Carl D. 

TITLE=Recurrent Isolated Oculomotor Nerve Palsy after Radiation of a Mesencephalic Metastasis. Case Report and Mini Review

JOURNAL=Frontiers in Neurology

VOLUME=5

YEAR=2014

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2014.00123

DOI=10.3389/fneur.2014.00123

ISSN=1664-2295

ABSTRACT=<p><bold>Introduction:</bold> Recurrent oculomotor nerve palsies are extremely rare clinical conditions.</p><p><bold>Case report:</bold> Here, we report on a unique case of a short-lasting recurrent unilateral incomplete external and complete internal oculomotor nerve palsy. The episodic palsies were probably caused by an ipsilateral mesencephalic metastasis of a breast carcinoma and occurred after successful brain radiation therapy.</p><p><bold>Discussion:</bold> While the pathogenic mechanism remains unclear, the recurrent sudden onset and disappearance of the palsies and their decreasing frequency after antiepileptic treatment suggest the occurrence of epilepsy-like brainstem seizures. A review of case reports of spontaneous reversible oculomotor nerve palsies is presented.</p>