AUTHOR=Djurfeldt Mikael , Ekeberg Örjan , Lansner Anders TITLE=Large-scale modeling - a tool for conquering the complexity of the brain JOURNAL=Frontiers in Neuroinformatics VOLUME=2 YEAR=2008 URL=https://www.frontiersin.org/journals/neuroinformatics/articles/10.3389/neuro.11.001.2008 DOI=10.3389/neuro.11.001.2008 ISSN=1662-5196 ABSTRACT=

Is there any hope of achieving a thorough understanding of higher functions such as perception, memory, thought and emotion or is the stunning complexity of the brain a barrier which will limit such efforts for the foreseeable future? In this perspective we discuss methods to handle complexity, approaches to model building, and point to detailed large-scale models as a new contribution to the toolbox of the computational neuroscientist. We elucidate some aspects which distinguishes large-scale models and some of the technological challenges which they entail.