AUTHOR=Hider Robert , Kleissas Dean , Gion Timothy , Xenes Daniel , Matelsky Jordan , Pryor Derek , Rodriguez Luis , Johnson Erik C. , Gray-Roncal William , Wester Brock 

TITLE=The Brain Observatory Storage Service and Database (BossDB): A Cloud-Native Approach for Petascale Neuroscience Discovery

JOURNAL=Frontiers in Neuroinformatics

VOLUME=16

YEAR=2022

URL=https://www.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2022.828787

DOI=10.3389/fninf.2022.828787

ISSN=1662-5196

ABSTRACT=<p>Technological advances in imaging and data acquisition are leading to the development of petabyte-scale neuroscience image datasets. These large-scale volumetric datasets pose unique challenges since analyses often span the entire volume, requiring a unified platform to access it. In this paper, we describe the Brain Observatory Storage Service and Database (<monospace>BossDB</monospace>), a cloud-based solution for storing and accessing petascale image datasets. <monospace>BossDB</monospace> provides support for data ingest, storage, visualization, and sharing through a RESTful Application Programming Interface (API). A key feature is the scalable indexing of spatial data and automatic and manual annotations to facilitate data discovery. Our project is open source and can be easily and cost effectively used for a variety of modalities and applications, and has effectively worked with datasets over a petabyte in size.</p>