AUTHOR=Wang Mengyue , Li Chunlin , Zhang Wenjing , Wang Yonghao , Feng Yuan , Liang Ying , Wei Jing , Zhang Xu , Li Xia , Chen Renji TITLE=Support Vector Machine for Analyzing Contributions of Brain Regions During Task-State fMRI JOURNAL=Frontiers in Neuroinformatics VOLUME=13 YEAR=2019 URL=https://www.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2019.00010 DOI=10.3389/fninf.2019.00010 ISSN=1662-5196 ABSTRACT=

The mainstream method used for the analysis of task functional Magnetic Resonance Imaging (fMRI) data, is to obtain task-related active brain regions based on generalized linear models. Machine learning as a data-driven technical method is increasingly used in fMRI data analysis. The language task data, including math task and story task, of the Human Connectome Project (HCP) was used in this work. We chose a linear support vector machine as a classifier to classify math and story tasks and compared them with the activated brain regions of a SPM statistical analysis. As a result, 13 of the 25 regions used for classification in SVM were activated regions, and 12 were non-activated regions. In particular, the right Paracentral Lobule and right Rolandic Operculum which belong to non-activated regions, contributed most to the classification. Therefore, the differences found in machine learning can provide a new understanding of the physiological mechanisms of brain regions under different tasks.