AUTHOR=Rotenberg David J. , Chang Qing , Potapova Natalia , Wang Andy , Hon Marcia , Sanches Marcos , Bogetic Nikola , Frias Nathan , Liu Tommy , Behan Brendan , El-Badrawi Rachad , Strother Stephen C. , Evans Susan G. , Mikkelsen Jordan , Gee Tom , Dong Fan , Arnott Stephen R. , Laing Shuai , Dharsee Moyez , Vaccarino Anthony L. , Javadi Mojib , Evans Kenneth R. , Jankowicz Damian 

TITLE=The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

JOURNAL=Frontiers in Neuroinformatics

VOLUME=12

YEAR=2018

URL=https://www.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2018.00077

DOI=10.3389/fninf.2018.00077

ISSN=1662-5196

ABSTRACT=<p>Investigations of mental illness have been enriched by the advent and maturation of neuroimaging technologies and the rapid pace and increased affordability of molecular sequencing techniques, however, the increased volume, variety and velocity of research data, presents a considerable technical and analytic challenge to curate, federate and interpret. Aggregation of high-dimensional datasets across brain disorders can increase sample sizes and may help identify underlying causes of brain dysfunction, however, additional barriers exist for effective data harmonization and integration for their combined use in research. To help realize the potential of multi-modal data integration for the study of mental illness, the Centre for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment—the <italic>CAMH Neuroinformatics Platform—</italic>based on the Ontario Brain Institute (OBI) Brain-CODE architecture, towards the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.</p>