AUTHOR=Wang Yinghua , Yan Jiaqing , Wen Jianbin , Yu Tao , Li Xiaoli 

TITLE=An Intracranial Electroencephalography (iEEG) Brain Function Mapping Tool with an Application to Epilepsy Surgery Evaluation

JOURNAL=Frontiers in Neuroinformatics

VOLUME=10

YEAR=2016

URL=https://www.frontiersin.org/journals/neuroinformatics/articles/10.3389/fninf.2016.00015

DOI=10.3389/fninf.2016.00015

ISSN=1662-5196

ABSTRACT=<p><bold>Objects</bold>: Before epilepsy surgeries, intracranial electroencephalography (iEEG) is often employed in function mapping and epileptogenic foci localization. Although the implanted electrodes provide crucial information for epileptogenic zone resection, a convenient clinical tool for electrode position registration and Brain Function Mapping (BFM) visualization is still lacking. In this study, we developed a BFM Tool, which facilitates electrode position registration and BFM visualization, with an application to epilepsy surgeries.</p><p><bold>Methods</bold>: The BFM Tool mainly utilizes electrode location registration and function mapping based on pre-defined brain models from other software. In addition, the electrode node and mapping properties, such as the node size/color, edge color/thickness, mapping method, can be adjusted easily using the setting panel. Moreover, users may manually import/export location and connectivity data to generate figures for further application. The role of this software is demonstrated by a clinical study of language area localization.</p><p><bold>Results</bold>: The BFM Tool helps clinical doctors and researchers visualize implanted electrodes and brain functions in an easy, quick and flexible manner.</p><p><bold>Conclusions</bold>: Our tool provides convenient electrode registration, easy brain function visualization, and has good performance. It is clinical-oriented and is easy to deploy and use. The BFM tool is suitable for epilepsy and other clinical iEEG applications.</p>