AUTHOR=Galindo-Romero Caridad , Norte-Muñoz María , Gallego-Ortega Alejandro , Rodríguez-Ramírez Kristy T. , Lucas-Ruiz Fernando , González-Riquelme María Josefa , Vidal-Sanz Manuel , Agudo-Barriuso Marta 

TITLE=The retina of the lab rat: focus on retinal ganglion cells and photoreceptors

JOURNAL=Frontiers in Neuroanatomy

VOLUME=16

YEAR=2022

URL=https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2022.994890

DOI=10.3389/fnana.2022.994890

ISSN=1662-5129

ABSTRACT=<p>Albino and pigmented rat strains are widely used in models to study retinal degeneration and to test new therapies. Here, we have summarized the main topographical and functional characteristics of the rat retina focussing on photoreceptors and retinal ganglion cells (RGCs), the beginning and end of the retinal circuitry, respectively. These neurons are very sensitive to injury and disease, and thus knowing their normal number, topography, and function is essential to accurately investigate on neuronal survival and protection.</p>