AUTHOR=Insausti Ricardo , Muñoz-López Mónica , Insausti Ana M. , Artacho-Pérula Emilio TITLE=The Human Periallocortex: Layer Pattern in Presubiculum, Parasubiculum and Entorhinal Cortex. A Review JOURNAL=Frontiers in Neuroanatomy VOLUME=11 YEAR=2017 URL=https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2017.00084 DOI=10.3389/fnana.2017.00084 ISSN=1662-5129 ABSTRACT=
The cortical mantle is not homogeneous, so that three types of cortex can be distinguished: allocortex, periallocortex and isocortex. The main distinction among those three types is based on morphological differences, in particular the number of layers, overall organization, appearance, etc., as well as its connectivity. Additionally, in the phylogenetic scale, this classification is conserved among different mammals. The most primitive and simple cortex is the allocortex, which is characterized by the presence of three layers, with one cellular main layer; it is continued by the periallocortex, which presents six layers, although with enough differences in the layer pattern to separate three different fields: presubiculum (PrS), parasubiculum (PaS), and entorhinal cortex (EC). The closest part to the allocortex (represented by the subiculum) is the PrS, which shows outer (layers I–III) and inner (V–VI) principal layers (