AUTHOR=Roe Anna Wang , Chernov Mykyta M. , Friedman Robert M. , Chen Gang TITLE=In Vivo Mapping of Cortical Columnar Networks in the Monkey with Focal Electrical and Optical Stimulation JOURNAL=Frontiers in Neuroanatomy VOLUME=9 YEAR=2015 URL=https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2015.00135 DOI=10.3389/fnana.2015.00135 ISSN=1662-5129 ABSTRACT=

There are currently largescale efforts to understand the brain as a connection machine. However, there has been little emphasis on understanding connection patterns between functionally specific cortical columns. Here, we review development and application of focal electrical and optical stimulation methods combined with optical imaging and fMRI mapping in the non-human primate. These new approaches, when applied systematically on a large scale, will elucidate functionally specific intra-areal and inter-areal network connection patterns. Such functionally specific network data can provide accurate views of brain network topology.