AUTHOR=Liu Yang , Huang Ying , Lee Syann , Bookout Angie L., Castorena Carlos M., Hu Wua , Gautron Laurent TITLE=PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges JOURNAL=Frontiers in Neuroanatomy VOLUME=9 YEAR=2015 URL=https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2015.00120 DOI=10.3389/fnana.2015.00120 ISSN=1662-5129 ABSTRACT=
Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription factor that was originally identified as a regulator of peroxisome proliferation and adipocyte differentiation. Emerging evidence suggests that functional PPARγ signaling also occurs within the hypothalamus. However, the exact distribution and identities of PPARγ-expressing hypothalamic cells remains under debate. The present study systematically mapped PPARγ mRNA expression in the adult mouse brain using