AUTHOR=Onishi Taichi , Hirose Kenzo , Sakaba Takeshi 

TITLE=Molecular tools to capture active neural circuits

JOURNAL=Frontiers in Neural Circuits

VOLUME=18

YEAR=2024

URL=https://www.frontiersin.org/journals/neural-circuits/articles/10.3389/fncir.2024.1449459

DOI=10.3389/fncir.2024.1449459

ISSN=1662-5110

ABSTRACT=<p>To understand how neurons and neural circuits function during behaviors, it is essential to record neuronal activity in the brain <italic>in vivo</italic>. Among the various technologies developed for recording neuronal activity, molecular tools that induce gene expression in an activity-dependent manner have attracted particular attention for their ability to clarify the causal relationships between neuronal activity and behavior. In this review, we summarize recently developed activity-dependent gene expression tools and their potential contributions to the study of neural circuits.</p>