AUTHOR=McKissick Olivia , Klimpert Nell , Ritt Jason T. , Fleischmann Alexander TITLE=Odors in space JOURNAL=Frontiers in Neural Circuits VOLUME=18 YEAR=2024 URL=https://www.frontiersin.org/journals/neural-circuits/articles/10.3389/fncir.2024.1414452 DOI=10.3389/fncir.2024.1414452 ISSN=1662-5110 ABSTRACT=

As an evolutionarily ancient sense, olfaction is key to learning where to find food, shelter, mates, and important landmarks in an animal’s environment. Brain circuitry linking odor and navigation appears to be a well conserved multi-region system among mammals; the anterior olfactory nucleus, piriform cortex, entorhinal cortex, and hippocampus each represent different aspects of olfactory and spatial information. We review recent advances in our understanding of the neural circuits underlying odor-place associations, highlighting key choices of behavioral task design and neural circuit manipulations for investigating learning and memory.